Damage to DNA in cancer cells can lead to pieces breaking off chromosomes and floating away, like icebergs cracking off a glacier. Just as icebergs are a threat to ships and their crew, these ...

Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a ...

R-loops are structures that form when a strand of RNA (red) forms a stable structure with double-stranded DNA, causing one strand of the DNA to form a loop. R-loops are associated with gene ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

It's tricky to make an exact copy of yourself. Or at least it is for cells undergoing mitosis, where cells replicate everything inside of them, including their neatly packaged DNA, then split in half.