Gene editing can repair mutations that prematurely halt protein synthesis, resulting in incomplete peptides that cause various diseases. However, other approaches achieve the same effect without ...

Systematic characterization of terminating ribosomes uncovers sequence features influencing ribosome dynamics at stop codons with direct implications in 3' UTR translation.

The DNA of nearly all life on Earth contains many redundancies, and scientists have long wondered whether these redundancies served a purpose or if they were just leftovers from evolutionary processes ...

Somewhere in a sample of ordinary pond water, a single-celled organism has been quietly breaking one of biology’s most fundamental rules. Condylostoma magnum, a free-living ciliate barely visible to ...

In April 2021, Jamie McGowan was running a routine test. A computational biologist at the Earlham Institute in Norwich, England, McGowan had fed a single-celled organism’s genetic data into a ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...