The opioid epidemic has claimed more than half a million lives in the U.S. since 1999, about three-quarters of them men, according to the National Institutes of Health. Although men's disproportionate ...

Could sex hormones explain the difference in opioid use and misuse between genders? Since 1999, the American opioid epidemic has killed more than half a million people, and according to the National ...

A team at the University of Houston, led by researcher Colin N. Haile, has built and tested a vaccine designed to train the ...

While opioids are incredibly powerful pain management tools, they can also be highly addictive. Since 2013, the rate of deaths from an overdose due to synthetic opioids, like fentanyl, has steadily ...

While the opioid epidemic is one of the most urgent public health emergencies facing the U.S., new therapeutic approaches for treating the underlying substance use disorder have lagged far behind.

Brain cells (magenta) in the reward center of a rat’s brain release dopamine in response to opioids. According to a new study by WashU Medicine researchers, male and female rats with a chronic pain ...