The interaction between Hertwig's epithelial root sheath (HERS) and surrounding mesenchymal cells is crucial for root dentin formation. HERS influences tooth root development and odontoblast ...

Tooth root development relies on precise coordination of cellular signals, yet the underlying mechanisms remain unclear. Researchers have uncovered how two proteins, Gli2 and Gli3, work together to ...

Teeth function not only because of the hard enamel on the surface, but also because they have roots that anchor them firmly in the jawbone beneath the gums. Eating, speaking, and maintaining the shape ...

A novel study on the natural coordination of tooth development in time and space, led by Dr. Han-Sung Jung at the Yonsei University College of Dentistry, Korea, has discovered that "lingual" cells on ...

Tooth loss affects billions worldwide. A Kyoto University spinout is testing a drug called TRG-035 that could regrow real ...

Japanese biotech drug aims to reverse tooth loss by regrowing teeth. Here's how TRG-035 works, where trials stand and when it ...

Scientists are uncovering a surprising link between hidden tooth infections and blood sugar problems. Deep infections around tooth roots can create chronic inflammation that spreads through the body ...

Completely dislodging a tooth from the socket is not generally considered a reversible process. However, this injury is most common in children, whose roots may not be completely developed, meaning ...

Sometimes, a tooth can become so severely damaged or infected that your dentist might discuss a couple of different kinds of treatment plans with you. The first is a root canal, and the other is a ...